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35 were preclinical (animal studies)

Methionine synthase facilitates the conversion of homocysteine into methionine, which is vital for producing various molecules, including phospholipids and neurotransmitters, as well as for regulating gene expression

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for patients experiencing: Pernicious anemia, with or without nervous system involvement Dietary B12 deficiency, including strict vegetarians and vegans Malabsorption of B12 due to stomach or intestinal issues affecting intrinsic factor General B12 deficiency symptoms, such as fatigue or neurological changes Administration Dosing depends on the severity of the patients deficiency and their clinical response

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