MNT spoke with Jeffrey Zarin, MD, an orthopedic surgeon specializing in joint replacement surgery at Cedars-Sinai Orthopaedics in Los Angeles, CA, about this study, who commented that his first reaction was to be cautious about over-interpreting its findings
Similarly, cytokines released in the brain can enter the systemic circulation and promote inflammation in the cardiovascular system, increasing the risk of CVDs
PMID: 8976642
In this analysis, we matched new users of GLP-1RAs to new metformin users on propensity scores
It is important to remember, however, that this trial was an open-label study that is to say, the participants knew that they were receiving the exenatide treatment so there is the possibility of a placebo effect explaining the improvements