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La administracin prolongada en humanos reduce selectivamente la masa grasa total (33,9%) y la masa grasa visceral (40%), preservando proporcionalmente la masa magra
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N Engl J Med 338:265266 Mannucci E, Ognibene A, Cremasco F et al (2001) Effect of metformin on glucagon-like peptide 1 (GLP-1) and leptin levels in obese non-diabetic subjects
How It Works : Tirzepatide mimics the actions of incretin hormones, which are released by the gut in response to food intake
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