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[12] [13] The medication works through a dual mechanism of action
Diabetologia 59(3):533541
Subcutaneous semaglutide 2.4 mg, a glucagon-like peptide 1 analogue, has been approved by the European Medicines Agency as an adjunct to a reduced-calorie diet and increased physical activity (diet and exercise [D&E]) for the treatment of obesity
It is also a GLP-1 receptor agonist, but it has a dual agonist effect, meaning that it targets both the GLP-1 receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor
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A detailed understanding of TNF signaling is essential for addressing these clinical obstacles (161)
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