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In a study by Ji et al., a novel group of -amino pyrrole-2-carbonitrile analogs was developed as selective DPP-4 inhibitors, with compound 55 (Figure 7) identified as the most potent, exhibiting an IC 50 value of 0.01 M

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CJC-1295 provides the GHRH signal while Ipamorelin amplifies it through the ghrelin receptor

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