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Upon appearance of clinical signs of VSV replication in the central nervous system, such as paralysis, mice were removed from the experiment
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The UPR, which shares molecular machinery with the integrated stress response, halts cap-dependent translation, induces expression of ER chaperone proteins and can lead to death if the stress is not resolved
doi: 10.1016/j.clim.2023.109818 115 TangHPangS