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This personalization is typically unavailable through insurance-covered care, making it a unique advantage of direct-access GLP-1 therapy
For that reason, it is imperative that baseline examination for the initiation of GLP-1 therapy assess for known/existing as well as potential high-risk patient cases
Semaglutide showed fewer serious adverse events compared to placebo in long-term studies
These may include: Bloating Abdominal pain Constipation Dizziness Diarrhea Headache Fatigue Indigestion Gastroenteritis Injection site reactions Nausea and vomiting These side effects are temporary and tend to last up to a few weeks
FDA-approved options for chronic weight management include: Other GLP-1 receptor agonists (semaglutide, liraglutide) Combination therapies (phentermine-topiramate ER, naltrexone-bupropion ER) Orlistat Metformin for patients with diabetes or prediabetes, which provides modest weight-neutral or weight-loss effects Realistic expectations are essential
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