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Genetic loss of Nrf1 and Nrf2 leads to distinct metabolism reprogramming of HepG2 cells by opposing regulation of the PI3K-AKT-mTOR signalling pathway
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Vion AC, Perovic T, Petit C, Hollfinger I, Bartels-Klein E, Frampton E, Gordon E, Claesson-Welsh L, Gerhardt H (2021) Endothelial cell orientation and polarity are controlled by shear stress and VEGF through distinct signaling pathways
To be clear, any claims regarding therapeutic benefits are based on preliminary findings in non-human models
Finerenone and left ventricular hypertrophy in chronic kidney disease and type 2 diabetes
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