Leggio L et al
RNA extraction and RTqPCR Total RNA from cells was isolated via TRIzol (Takara, Otsu, Japan) and subsequently purified with chloroform/isopropanol/ethanol, and cDNA was synthesized via the PrimeScript RT reagent Kit (Takara) according to the manufacturers instructions and used as the template for qRTPCR

Dimer Dilinoleyl Dimer Dilinoleate, Cocos Nucifera (Coconut) Oil, Polyhydroxystearic Acid, Polyglyceryl-6 Polyricinoleate, Euphorbia Cerifera (Candelilla) Wax, Theobroma Cacao (Cocoa) Seed Butter, Caprylic/Capric Triglyceride, Simmondsia Chinensis (Jojoba) Seed Oil, Silica, Tetrahexyldecyl Ascorbate, Punica Granatum Flower Extract, Polyglyceryl-3 Diisostearate, Stearalkonium Hectorite, Propylene Carbonate, Dipotassium Glycyrrhizate, Tocopherol, Sodium Hyaluronate, Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil (+/-): Titanium Dioxide (CI 77891), Iron Oxides (CI 77491, CI 77492, CI 77499), Red 6 (CI 15850), Red 7 Lake (CI 15850), Blue 1 Lake (CI 42090), Yellow 6 Lake (CI 15985), Manganese Violet (CI 77742)
Melanotan 2 also activates MC1R, but it doesnt stop there
We first came across LightEyez in early 2023 and reported them to the FDA