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"But pretreatment with NAC increased glutathione levels in the older cells and largely helped offset that level of cell death." Glutathione, Hagen said, is such an important antioxidant that its existence appears to date back as far as oxygen-dependent, or aerobic life itself - about 1.5 billion years
doi:10.1006/bbrc.1994.1643
who demonstrated that the blockade of lactate transport exacerbates neuronal damage after ischemia in a rodent model of global ischemia 45
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