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The safest current interpretation is that methylation-related concerns are biologically plausible and relevant to study design, but they are not established as consistent toxicological findings for 5-Amino-1MQ under all published preclinical conditions
The subcutaneous route is good for those who cant get intramuscular shots or have certain health issues
They're easier and usually without the risks of a vitamin B12 shot
Attia, P
The shot itself takes seconds, plus a couple of minutes of intake
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