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Increased energy expenditure One of the most important theoretical advantages of glucagon receptor activation is increased energy expenditure
Conclusion As the multi-hit hypothesis holds, combining the therapeutic approaches of GLP-1 agonists with resmetirom seems like a promising strategy by targeting the multifaceted pathophysiology of MASH, which may lead to improved patient outcomes
Robert, 1979
In future research, more human cohort studies can be conducted to correlate TMAO levels with IBD phenotypes through multi-omics analysis
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