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Indeed, China, the USA, and Brazil published many articles on AFG1 and ranked first to third countries to conduct research in this area

This, in turn, has been demonstrated to result in the up-regulation of PD-L1 expression, the reduction of CD4 and CD8 T-cell activation and tumor infiltration, and the promotion of the growth of pancreatic ductal adenocarcinoma (PDAC) cells [112]

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Hurot JM, Cucherat M, Haugh M, Fouque D