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The 10mg dose produces 1517% mean weight loss at 72 weeks, which meets clinical significance thresholds and exceeds lifestyle intervention outcomes in 95% of cases

Blood glucose monitoring: Individual responses to caffeine vary, with some people experiencing temporary effects on blood glucose

Wu D et al

[12] The approved dosing for both indications involves subcutaneous injection once weekly, with gradual dose escalation from 2.5 mg to maintenance doses of 5 mg, 10 mg, or 15 mg based on individual response and tolerability

Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: the STEP 3 Randomized Clinical Trial