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Compared to lifestyle changes alone, GLP-1 medications can significantly improve weight loss outcomes for individuals with PCOS

This sounds like a benefit, and it is, up to a point

Eli Lilly just hit that with a weekly shot

Feeding diabetes-prone BioBreeding (BBdp) rats a hydrolyzed casein-based diet, a diet that binds nutritional copper and lowers tissue copper, promotes islet cell neogenesis and results in 23-fold fewer diabetes cases compared with feeding cereal-based diets [ 43 ]

So they're obese because they're type 2 diabetic