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Since ROC curves are a continuous-scale display, a cut-off point is chosen to allow comparisons between different studies output, such as a typically fixed value of 80% for sensitivity or specificity
This map could help reveal new therapeutic targets and inform early interventions for type 1 diabetes before insulin production is impaired in at-risk children
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IGF1 LR3s half-life is approximately 20 to 30 hours (native IGF1lasts 1215 hours)
SURMOUNT-4 demonstrated that stopping tirzepatide led to regain of 14 percentage points of body weight over 52 weeks versus ongoing treatment [10]
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![Structures of (a) GLP-1, (b) GIP and (c) tirzepatide [19, 88, 90]](https://www.researchgate.net/publication/370926483/figure/fig4/AS:11431281185432337@1693619320519/Structures-of-a-GLP-1-b-GIP-and-c-tirzepatide-19-88-90-Amino-acids-are.png)
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