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Description

Four effects explain most of what these drugs do: 1

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Inhibition of lipid oxidation increases glucose metabolism and enhances 2-deoxy-2-[(18)F]fluoro-D-glucose uptake in prostate cancer mouse xenografts

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Autophagy exhibits selectivity in degrading certain cargoes such as mitochondria (mitophagy) endoplasmic reticulum (reticulophagy), intracellular microbes (xenophagy), lipid droplets (lipophagy), peroxisomes (pexophagy) and glycogen (glyophagy) or non-selective to degrade random parts of the cytoplasm (144)

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