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Both compounds are injected subcutaneously, just under the skin
In an ad-libitum meal experiment with varying fat content, patients with MC-4R mutations consumed 95% more of the high-fat meal compared to lean controls, and 65% more compared to obese controls
There is no "window" where the medication has worn off and your blood work reflects your unmedicated baseline
For those who are injection-averse, the psychological barrier alone can be enough to delay or avoid treatment entirely
The reduction of pro-inflammatory cytokines, improvement in intestinal barrier integrity, and potential modulation of gut microbiota composition represent mechanisms that could theoretically complement existing IBD therapies
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