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One such example is glucagon-like peptide 1 (GLP-1) (3.3 kDa), a small peptide hormone with a plasma half-life of only two minutes due to enzymatic degradation by dipeptidyl peptidase-4 (DDP-4) in the blood and rapid excretion through the kidneys 16,17,18,19

13 In other words, GLP-1 medicines reduce disease complications directly and indirectly in overlapping ways, perhaps most importantly by reducing chronic inflammation

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