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The trial escalation tables stepped the amount up on a monthly cadence, beginning in the low single-digit milligram range and only advancing once the prior level felt comfortable

The study compared three administration routes intraperitoneal, oral (in drinking water), and topical (thin cream layer) all delivered without a carrier

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8YW3: Li W, Zhou Q, Cong Z, Yuan Q, Li W, Zhao F, Xu HE, Zhao LH, Yang D, Wang MW