As we all know, Eli Lilly is close behind in the race with its oral GLP-1, orforglipron, which is expected to be approved by the FDA late in the first quarter
ABCG2 dysfunction caused by common variants will significantly increase the risk of hyperuricaemia, and the reduction of extra renal urate excretion through dysfunctional ABCG2 is a common mechanism of hyperuricaemia (Ichida et al., 2012)
NICE prioritises SGLT2 inhibitors for people with established or high risk of cardiovascular or kidney disease, with GLP-1 receptor agonists considered in specific scenarios, particularly when weight loss is desired
Keeping track of how much protein you eat also helps you plan balanced meals with the right mix of carbs, fats, and proteins for continued weight loss success
Peeters F, Cassiman C, Van Keer K, Levtchenko E, Veys K, Casteels I (2019) Ophthalmic outcome in a Belgian cohort of cystinosis patients treated with a compounded preparation of cysteamine eye drops: retrospective analysis