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Pissios P., Nicotinamide N-methyltransferase: more than a vitamin B3 clearance enzyme, Trends Endocrinol Metab, 2017

The chaperone HSPB1 prepares protein aggregates for resolubilization by HSP70

Moreover, pericardial fluid has gained growing interest for the diagnosis and treatment of CVDs due to its anatomical proximity to the myocardium, its low clearance rates and origin as output of plasma ultrafiltration from the epicardial capillaries, secretions from pericardial mesothelial cells and contributions of the myocardial interstitial space 37

[1] Some compounders suggest adding B12 to tirzepatide formulations based on theoretical concerns about vitamin B12 absorption, though it's important to note that clinical evidence specifically linking tirzepatide to B12 deficiency is lacking