Armstrong, Annalee, The Megaround Ruled Biopharma in 2024 as First-Time VC Funding Doubled, BioSpace, 9 Jan, 2025, 15
Adipose tissue plays a role in hormone metabolism, and substantial changes in body composition may temporarily affect hormonal balance
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Meanwhile, inflammatory mediators and oxidative products generated in the lungs can enter the systemic circulation, triggering a state of chronic, low-grade systemic inflammation that facilitates the development and progression of multiple extrapulmonary comorbidities, including cardiovascular diseases, immune dysregulation, skeletal muscle wasting, and metabolic abnormalities (Patra et al., 2025