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Inflammatory response of the exposed fish showed changes in the IL-1, IL-6, TNF-, TGF-, NF-B, and p65 and immune parameters (IgM, LYZ, ACP, C3, and AKP), indicating that PYR exposure caused an induction in apoptosis due to oxidative stress and also evoked inflammation and immunotoxicity in common carp (Zhao et al., 2022)
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GSH levels in whole blood, erythrocytes, plasma and peripheral blood mononuclear cells (PBMCs) were assessed in 12 subjects at the baseline and after 1, 2 and 4 weeks of GSH administration
(See figure below showing the methylation and transsulfuration pathways.) Glutathione production starts with the amino acid cysteine
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