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An Evidence-Based Perspective Key Points GLP-1 medications are safe from a psychiatric perspective and dont increase risk of depression or suicidality These medications improve mental health-related quality of life and eating behaviors beyond their effects on weight Lower doses combined with comprehensive psychological and lifestyle support produce excellent results with minimal side effects GLP-1s reduce inflammation, which directly benefits mood and neurotransmitter function Psychiatrists are well-positioned to prescribe GLP-1s as part of integrated metabolic-psychiatric care I want to address a question that comes up constantly in psychiatric circles right now
If your employer plan excludes anti-obesity drugs: Explore the OSA pathway if applicable
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Splitting a dose across the week Some providers prescribe split dosing, where the weekly dose is divided into two injections given 3 to 4 days apart
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