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In this review, the term redox bottleneck is used as a conceptual framework describing conditions in which oxidative throughput approaches the regenerative capacity of substrate-supported NAD/NADPH-dependent buffering systems under sustained energy flux constriction
This includes SSRIs (such as Zoloft, Prozac, Celexa, and Paxil), SNRIs (such as Effexor and Savella), MAOIs, tricyclic antidepressants, and some mood stabilizers like lithium
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