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Zhang et al., 2012)

8.0 MET scores were assigned for one minute of vigorous work-related activity and vigorous leisure-time physical activity, while 4.0 MET scores were assigned for one minute of moderate work-related activity, walking or bicycling for transportation, and moderate leisure-time (recreational) physical activity

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Furthermore, data concerning the occurrence of the meiotic error (MI or MII), the maternal age at conception, as well as smoking and drinking habits, are often unavailable in case-control studies, making it impossible to evaluate their contribution during the meta-analysis (Table 2)

it slows gastric emptying and signals satiety to the brainstem and hypothalamus, reducing food intake