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However, further in vitro assays and preclinical studies with this NP-delivered metal chelator approach are warranted to improve their targeting capacity to the brain as well as to estimate the level of BBB crossing, chelation efficiency and the related toxicity before clinical applications
Exceptionally stable due to triple proline sequence (Pro-Pro-Pro) providing structural rigidity and protease resistance
Nature 493, 542546
G.RepanaD.et al
The reduced GSH and the oxidized one (GSSG) are the most prominent types of thiol which are widely used as indicators for evaluating the oxidative stress level
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