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Lysine, taken as a dietary supplement, can cause gastrointestinal side effects

Metabolic issues: Feeling constantly cold, chills, or a low body temperature (signs of metabolic acidosis) Severe gastrointestinal changes: Persistent diarrhea, vomiting, or a total loss of appetite Systemic changes: Unexplained tiredness, a fever or other signs of infection, unusual bleeding, bruising, or long-term concerns like osteoporosis In general, higher doses of topiramate are associated with an increased risk of adverse reactions

Poor sleep can also dull fullness cues, making it easy to eat more than you need, while making blood sugar harder to keep steady

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