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Phase 2 trials investigated doses of 1 mg, 4 mg, 8 mg, and 12 mg administered as once-weekly subcutaneous injections
The hyperinsulinemia in ob/ob mice might be caused by the impairment of leptin signaling in pancreatic -cells and contributes to obesity and insulin resistance
doi: 10.1093/chemse/bjac004, 149 TuestaL
Each syringe should be drawn and injected in the same session
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