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Ipamorelin a selective ghrelin receptor agonist emerged from studies in the 1990s investigating ghrelin mimetics and their ability to stimulate growth hormone release with minimal off-target hormonal effects

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Importantly, both functional recovery and reduction of fibrotic scarring were more pronounced in the high-dose curcumin group compared with the medium-dose group, suggesting a dose-dependent effect

10.1016/s0140-6736(14)61838-61839 Lancet 142 WuH.TaoJ.LiX.ZhangT.ZhaoL.WangY.et al (2017)

The research and formulation guidance converge on specific ranges that balance efficacy with safety