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In HCT-116 cells, treatment with 20 M ginkgetin for 24 h enhanced p53 transcriptional activity and caused ferroptosis, as evidenced by a significant increase in iron content in cells and a significantly reduced GSH content and the strongest reversal effect caused by Fer-1 [48]
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Abstract Glutathione peroxidases (GPXs) are key reactive oxygen species (ROS) scavenging enzyme that catalyses the reduction of H 2 O 2 to prevent the cellular machinery from H 2 O 2 damage
It protects us from free radicals that affect cellular integrity, and we need a little more glutathione to defend our system as we get older
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