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NNMT normally burns through NAD+ precursors as a kind of metabolic "bleed." Block the bleed, and MOTS-C's expanded mitochondrial activity has more substrate to work with
Moving to 12mg, if needed, should happen only after successful tolerance at 8mg for at least four weeks
Every one of those numbers is downstream of a single choice how much water you add so it is worth understanding what happens if that choice changes
However, in patients treated with diclofenac and glucocorticoids, the risk of peptic ulcer and gastrointestinal bleeding may increase, so special attention should be given in case of prolonged treatment, even in the absence of serious gastrointestinal symptoms
It should be noted that injectable versions of GHK-Cu are for research purposes only and are not intended for human use
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