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Most gastrointestinal side effects occur during the first month
True non-responders: uncertain outcomes If semaglutide produced absolutely no appetite suppression, no metabolic improvement, and no weight loss even at the maximum 2.4mg dose over 16 or more weeks, you may have fundamental resistance to GLP-1 receptor agonism
Compared with oral hypoglycemic drugs, patients' compliance with injectable drugs is relatively poor
This fat is more hormonally active and responds to different metabolic signals
Nausea, diarrhea, and vomiting are most common reactions, and they tend to spike during dose changes
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