glutathione peroxidase pathway Small molecule selenium-based 4 mimetic inhibits lipid peroxidation and protects cultured neurons from ferroptosis Oxytosis/Ferroptosis in Neurodegeneration: the Underlying

In conclusion, the study robustly demonstrated that FOXO4-DRI selectively eliminates senescent Leydig cells, reduces detrimental SASP factor secretion, improves the testicular microenvironment, and ultimately enhances sperm quality and spermatogenesis in aged mice, positioning it as a promising therapeutic candidate for age-related male infertility [2]

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34 There is mounting evidence that mitochondrial dysfunction may be present in a significant subset of children with autism and contribute to the multisystem abnormalities seen in some autistic children