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Notably, the inward movement of GIPR R300 5.40b contributed one hydrogen bond with T5 P (Fig

The ASCO GI 2026 data suggest that GLP-1 therapy may be particularly relevant for metabolically high-risk populations, including individuals with obesity, insulin resistance, or type 2 diabetesgroups that now account for a substantial proportion of colorectal cancer burden

Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2