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The clinical work doesn't wait for the literature to fully resolve

According to the company: ColonBroom advises against use if you have mood disorders, liver or kidney disease, or are pregnant or breastfeeding

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A sticky note on your bathroom mirror, a specific item moved to an unusual location (your coffee mug placed upside-down the night before), or a medication box with day-of-week labels

Obtaining prescription refills abroad is possible but complex, with success depending on destination country, medication type, and trip length