doi:10.3390/ijms19071987 8
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Lotte Bjerre Knudsen (32:02): I don't know about health span, but because certainly there's been so many studies with metformin and there's been a lot of wonderful data showing an effect on the epigenetic clocks, but not really an effect on lifespan because that metformin is so widely used
PubMed Zhang, L., Chopp, M., Lu, M., Zhang, T., Winter, S., Doppler, E., Meier, D., Chao, L., Eapen, A., Pabla, P., & Zhang, Z.G
To mitigate these effects, it's advisable to minimize the use of unnecessary medications as much as possible and seek out alternative treatment options that are less likely to disrupt gut health