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Candida-driven gut permeability allows bacterial lipopolysaccharides to activate thyroid antibody production, and mycotoxins impair the hepatic conversion of T4 to the active T3 form producing functional hypothyroid symptoms with or without abnormal TSH

However, these effects usually dissipate after a few weeks

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J.MedellinC.StieberA.RobinsonJ

Extrapolation from adult data cannot adequately address questions of optimal dosing, long-term safety across developmental stages, or effects on final adult height and peak bone mass, underscoring that dedicated pediatric research represents an urgent priority