semaglutide cvot and Cardiovascular Outcomes in Obesity Semaglutide and Cardiovascular Outcomes in

Kraemer, Am

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Both act on GLP-1 receptors, and combining them greatly increases the risk of severe GI side effects, hypoglycemia (in diabetes patients), and other adverse events, without providing additional clinical benefit

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Sodium-glucose transporter proteins (SGLT) are responsible for glucose and sodium co-transport by the luminal membrane of kidney cells