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Because TG2 activity is highly associated with cellular redox status and alterations in the bidirectional flux of cellular thiol modulate TG2 activity, regulation of thiol flux in cells probably affects the TG2-mediated aggregation of the GST tag and its interaction with cellular proteins
doi:10.1093/toxsci/kfr112
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If it goes the wrong way, it can hurt the stomach lining instead of helping with digestion
Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis
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