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I am not a chemist but B12 does seem to be an inherently stable molecule, not least indicated by the fact that the boxes of it have long shelf from production dates on them
Preparation and route: Injectable versus oral forms differ in bioavailability and stability
Gauge numbers move in the opposite direction of thickness, so the higher number is the thinner needle
It is synthesised in the cytosol by glutamate-cysteine ligase (EC 6.3.2.2) and glutathione synthetase, with the first, rate-limiting step feedback-inhibited by glutathione itself and intracellular concentrations typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999)
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