Pay in 4 interest-free payments of $6.90 Learn more
Ships within 48 hours · Estimated delivery Aug 30 - Sep 4
Sparks JA, Vanni KMM, Sparks MA, Xu C, Santacroce LM, Glynn RJ, Ridker PM, Solomon DH (2021) Effect of low-dose methotrexate on estimated glomerular filtration rate and kidney adverse events: a randomized clinical trial
27 , e13211 (2022)
1,2 The dose-by-dose data from the published trials: TRIUMPH-4s 18.2% discontinuation rate at 12 mg is more than three times higher than TRANSCEND-T2D-1s 5.1% on the same dose
The metabolic profile is very similar to that in column 3 except that now the intracellular SAH concentration does not decline but instead increases by 24% in line with the clinical data
doi: 10.1172/jci.insight.160345 15 MaloneAFWuHFronickCFultonRGautJPHumphreysBD
/product/99/7475523/1.jpg?7369)
/product/51/4175523/1.jpg?8625)