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Studies have found that people with the early stages of the condition also have low glutathione levels in a specific part of the brain

Antioxidants and lipid peroxidation status in diabetic patients with and without complications

Nonetheless, whether ferroptotic cell death is associated with the effects of GSH depletion on RPE is unknown

This is due to an impairment in dTMP synthesis which leads to cell cycle arrest in S-phase of rapidly proliferating cells, in particular hematopoietic cells