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The liver, which stores B12, can be compromised by excessive alcohol intake, leading to higher B12 requirements

Mischopoulou M, DAmbrosio M, Bigagli E, Luceri C, Farrugia G, Cipriani G (2022) Role of macrophages and mast cells as key players in the maintenance of gastrointestinal smooth muscle homeostasis and disease

Discontinuation rates were low and well-balanced among patients treated with VK2735 compared with placebo