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We determined that the enrollment of 3260 patients would be required to determine the primary outcome in at least 122 patients and provide a power of 90% to reject a hazard ratio of at least 1.80 at the 0.05 level of significance
This compound also influences satiety in the hypothalamus
This is where MeAgain's GLP-1 app fits in, it addresses this by logging medication timing, meals, hydration, and side effects so users and clinicians can spot symptom clusters and make informed adjustments
Although it is not clear how these injectables are causing NAION, it is hypothesized that the drugs effect on blood pressure and vascular tone may contribute to reduced blood flow to the optic nerve in susceptible users
PMID 21639810
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