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In addition, insulin regulates w-no-lysine (WNK) kinases, which, through the stimulation of sodium reabsorption in the distal nephron, are responsible for familial hypertension (112, 116)

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NA can instead be transported by SLC5A8 and SLC22A13 74,75 , while SLC7A5 and SLC36A4 are required for uptake of Trp 71,72

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