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Hence, T2D plays a vital role in CD development (Fig

As Imperial College Londons Ivan Koychev noted: People exposed to GLP-1RAs over many years appear to have a lower risk of ever developing dementia, which suggests an influence on the earliest pathogenic processes rather than on established neurodegeneration. 2

It has been observed that the GluN2B subunit, present in synaptic cytosol, plays a role in mediating the excitotoxic response (Wyllie, Livesey and Hardingham, 2013)

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In the UK, such products are regulated under the GB Cosmetic Products Regulation (retained from EU Regulation 1223/2009, overseen by the Office for Product Safety and Standards, OPSS)