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Broader Biological Effects Anti-inflammatory Potential : -MSH and its analogs, including MT1, have been shown to reduce pro-inflammatory cytokines and modulate immune responses, suggesting possible therapeutic roles beyond tanning
The SURPASS-3 MRI substudy added another layer, showing tirzepatide actually reduced muscle fat infiltration across all doses, indicating improved muscle quality even as total muscle volume decreased
These hormones trigger insulin release, suppress appetite, slow gastric emptying, and increase satiety (the feeling of fullness)
Without adequate protein to signal muscle preservation, the body takes both
Weight regain is a concern after discontinuing medication, highlighting the need for ongoing management
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