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In the present study, we used only male mice to minimize variability introduced by the estrous cycle in females, which is known to influence toxicity, body weight, food intake, and metabolic parameters [31,32,33,34,35,36]
It binds and unbinds in a constant exchange, so some free copper ions escape and irritate local nerve endings while activating mast cells (immune cells that release histamine and trigger inflammation)
vomiting: 5.5% to 15.7%
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after a year added in glutathione and had an immediate crash exactly like the previous one
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